missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Please login to your online account to display your discounted pricing
Thermo Scientific Chemicals Ouabain octahydrate, 96%
Ouabain octahydrate, CAS # 11018-89-6, (synonym: gamma-Strophanthin), is a plant-derived organic compound that inhibits the Na+/K+ ATPase pump present in all animal cell membranes.
Supplier: Thermo Scientific Chemicals 161730010
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• Ouabain octahydrate is a water-soluble, light-sensitive powder that is stable at ambient temperatures
• It is a glycoside comprised of rhamnose and ouabagenin, and is derived from the ripe seeds of Strophanthus gratus and the bark of Acokanthera ouabaio
Applications
• Ouabain octahydrate works by binding the Na+/K+ ATPase pump, thus disrupting its function, and leading to an increase in intracellular Na+.
• The inhibitory action of ouabain octahydrate on the Na+/K+ pump in cardiac cells makes it a pharmaceutical cardioactive agent
• Ouabain octahydrate has also been found to induce cytotoxic effects through a steroidal signal transduction pathway, in laboratory preparations
Specifications
| Ouabain octahydrate | |
| 260.0°C | |
| Authentic | |
| Glass bottle | |
| MFCD00149240 | |
| 15, V,5, 123 | |
| − 33.00 (20.00°C c=1,H2O,on dry subs.) | |
| ouabain octahydrate, strophantine octahydrate, quabain octahydrate, ouabain usp, penta a phenanthren-17-yl-2h-furan-5-one;octahydrate, gamma-strophanthin, 3-1r,3s,5s,8r,9s,10r,11r,13r,14s,17r-1,5,11,14-tetrahydroxy-10-hydroxymethyl-13-methyl-3-2r,3r,4r,5r,6s-3,4,5-trihydroxy-6-methyloxan-2-yl oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1h-cyclo, prestwick_370, acocantherine;g-strophanthin | |
| TYBARJRCFHUHSN-DMJRSANLSA-N | |
| 3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one;octahydrate | |
| 6364534 | |
| 96% |
| 11018-89-6 | |
| White | |
| 95% min. (HPLC) | |
| C29H44O12·8H2O | |
| 1 g | |
| 14, 6901 | |
| − 33.00 | |
| (1% in water) Clear colorless | |
| CC1C(C(C(C(O1)OC2CC(C3(C4C(CCC3(C2)O)C5(CCC(C5(CC4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O.O.O.O.O.O.O.O.O | |
| 728.78 | |
| 728.78 | |
| Crystalline Powder |
Chemical Identifiers
| 11018-89-6 | |
| 728.78 | |
| TYBARJRCFHUHSN-DMJRSANLSA-N | |
| 6364534 | |
| CC1C(C(C(C(O1)OC2CC(C3(C4C(CCC3(C2)O)C5(CCC(C5(CC4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O.O.O.O.O.O.O.O.O |
| C29H44O12·8H2O | |
| MFCD00149240 | |
| ouabain octahydrate, strophantine octahydrate, quabain octahydrate, ouabain usp, penta a phenanthren-17-yl-2h-furan-5-one;octahydrate, gamma-strophanthin, 3-1r,3s,5s,8r,9s,10r,11r,13r,14s,17r-1,5,11,14-tetrahydroxy-10-hydroxymethyl-13-methyl-3-2r,3r,4r,5r,6s-3,4,5-trihydroxy-6-methyloxan-2-yl oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1h-cyclo, prestwick_370, acocantherine;g-strophanthin | |
| 3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one;octahydrate |
Safety and Handling
GHS H Statement
Fatal if swallowed.
Toxic if inhaled.
May cause damage to organs through prolonged or repeated exposure.
GHS P Statement
Wear protective gloves/protective clothing/eye protection/face protection.
Get medical attention/advice if you feel unwell.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
GHS Signal Word: Danger
RUO – Research Use Only