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Osteopontin Mouse anti-Human, eFluor 660, Clone: 2F10, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $433.55

Specifications

Antigen Osteopontin
Clone 2F10
Host Species Mouse
Gene Alias bone sialoprotein I (BSP-1)
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124491

 
affymetrix
50909641
25 tests Each for $187.05

501124492

 
affymetrix
50909642
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen Osteopontin
Clone 2F10
Host Species Mouse
Gene Alias bone sialoprotein I (BSP-1)
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 660
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The 2F10 monoclonal antibody recognizes human osteopontin (OPN), a secreted glycophosphoprotein expressed by multiple cell types, including leukocytes, fibroblasts, dendritic cells, macrophages, myoblasts, bone-forming cells, and epithelial cells. OPN is an extracellular matrix protein with multiple roles, including bone resorption and calcification, immune system regulation, wound healing, and tumorigenesis. Thrombin cleavage of OPN allows binding of integrin receptors, expressed by immune cells, and subsequent modulation of cell adhesion, migration, and survival. OPN is expressed in bones, teeth, placenta, blood vessels, kidney, and various tumors. Osteopontin has been identified as a potential therapeutic target in the treatment of autoimmune disease, cancer metastasis, bone mineralization diseases, and osteoporosis.