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Alfa Aesar™ Orotic acid, anhydrous, 97%

$129.26 - $353.27

Chemical Identifiers

Chemical Name or Material Orotic acid
CAS 65-86-1
Name Note anhydrous
Molecular Formula C5H4N2O4
Formula Weight 156.10g/mol
MDL Number MFCD00006027
Synonym 1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid; Uracil-4-carboxylic acid
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAB2534922

 
alfa aesar™
B25349-22
100g Each for $129.26

AAB2534936

 
alfa aesar™
B25349-36
500g Each for $353.27
Description & Specifications

Specifications

Melting Point 344° to 347°C
Quantity 100g
Chemical Name or Material Orotic acid
Name Note anhydrous
CAS 65-86-1
Assay 97%
Molecular Formula C5H4N2O4
Formula Weight 156.10g/mol
MDL Number MFCD00006027
Synonym 1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid; Uracil-4-carboxylic acid
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
Health Hazard 3 GHS P Statement
P280-P305+P351+P338-P362-P301+P312-P321-P501a
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Take off contaminated clothing and wash before reuse.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Specific treatment (see label).
Dispose of contents/container in accordance with local/regional/national/international regulations.
RTECS Number RM3180000
TSCA TSCA

Applications
Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

Solubility
Slightly soluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Safety and Handling

Warning

GHS P Statement
P280-P305+P351+P338-P362-P301+P312-P321-P501a
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Take off contaminated clothing and wash before reuse.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Specific treatment (see label).
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.