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Alfa Aesar™ Orotic acid, anhydrous, 97%

$129.92 - $354.04

Chemical Identifiers

CAS 65-86-1
Molecular Formula C5H4N2O4
Formula Weight 156.1
MDL Number MFCD00006027
Synonym 1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid; Uracil-4-carboxylic acid
Chemical Name or Material Orotic acid, anhydrous
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAB2534922 SDS Alfa Aesar™
B2534922
100g Each for $129.92
AAB2534936 SDS Alfa Aesar™
B2534936
500g Each for $354.04
Specifications

Description

Applications
Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

Solubility
Slightly soluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Description & Specifications

Chemical Identifiers

65-86-1
156.1
1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid; Uracil-4-carboxylic acid
C5H4N2O4
MFCD00006027
Orotic acid, anhydrous

Specifications

156.1
MFCD00006027
C5H4N2O4
1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid; Uracil-4-carboxylic acid
97%
100g
344° to 347°C
65-86-1
Orotic acid, anhydrous

Safety and Handling

GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.

GHS P Statement
P280-P305+P351+P338-P362-P301+P312-P321-P501a
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Take off contaminated clothing and wash before reuse.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Specific treatment (see label).
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : RM3180000

TSCA : TSCA