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Oncostatin M Receptor Mouse anti-Human, PE, Clone: AN-V2, eBioscience™

Mouse Monoclonal Antibody

$404.55 - $404.55

Specifications

Antigen Oncostatin M Receptor
Clone AN-V2
Host Species Murine
Gene Alias OSMR
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010609 Life Technologies
LS12130342
100 Tests Each for $404.55
Specifications

Description

This monoclonal AN-V2 antibody reacts with the human oncostatin M (OSM) receptor. OSM, which belongs to the interleukin-6 cytokine family, is produced by T cells, activated monocytes, and dendritic cells. In humans, OSM can bind two unique receptor complexes. The type I OSM receptor is composed of the LIFR associated with gp130, and recognizes both LIF and OSM. The type II OSM receptor, which consists of gp130 and the OSMR subunit, specifically binds the cytokine, leading to activation of the JAK/STAT signaling pathway. Reports have also indicated a soluble form of the OSM receptor, which this antibody also recognizes. The OSM receptor is expressed in the bone marrow, endothelium, liver, lung, and numerous tumor cell lines.

The AN-V2 monoclonal antibody recognizes the type II (beta) OSM receptor.
Description & Specifications

Specifications

Oncostatin M Receptor
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
AN-V2
OSMR
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.5μg)/test