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Oncostatin M Receptor Mouse anti-Human, PE, Clone: AN-V2, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $404.55

Specifications

Antigen Oncostatin M Receptor
Clone AN-V2
Host Species Mouse
Gene Alias OSMR
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010608

 
affymetrix
12-1303-41
25 tests Each for $172.55

5010609

 
affymetrix
12-1303-42
100 tests Each for $404.55
Description & Specifications

Specifications

Antigen Oncostatin M Receptor
Clone AN-V2
Host Species Mouse
Gene Alias OSMR
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.5μg)/test

This monoclonal AN-V2 antibody reacts with the human oncostatin M (OSM) receptor. OSM, which belongs to the interleukin-6 cytokine family, is produced by T cells, activated monocytes, and dendritic cells. In humans, OSM can bind two unique receptor complexes. The type I OSM receptor is composed of the LIFR associated with gp130, and recognizes both LIF and OSM. The type II OSM receptor, which consists of gp130 and the OSMR subunit, specifically binds the cytokine, leading to activation of the JAK/STAT signaling pathway. Reports have also indicated a soluble form of the OSM receptor, which this antibody also recognizes. The OSM receptor is expressed in the bone marrow, endothelium, liver, lung, and numerous tumor cell lines.

The AN-V2 monoclonal antibody recognizes the type II (beta) OSM receptor.