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Thermo Scientific™ Lab Vision™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody


Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1849PABX

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Catalog No. MS1849PABX

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Description & Specifications

Specifications

Antigen Nucleophosmin (NPM) Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone NA24
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen GST fusion protein containing the N-terminal part of nucleophosmin fused to 14 aa of ALK protein
Isotype IgG kappa
Quantity 200µL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody.

Nucleophosmin (NPM)/B23/numatrin is a phosphoprotein associated with cell nucleoli. Treatment of cells with cytotoxic drugs may make nucleophosmin enter nucleoplasm. It is reported that nucleophosmin shuttles continuously between cytoplasm and nucleoli to carry newly synthesized ribosomal proteins into nucleoli. NPM-ALK is a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in anaplastic large cell lymphoma. In acute promyelocytic leukemia NPM gene is fused to RARalpha gene in (5;17) (q33;q12) transition.

Host Species: Mouse

Clone: NA24

Isotype: IgG/κ

Species Reactivity: Human. Others not known.

Epitope: N-terminal

Immunogen: GST fusion protein containing the N-terminal part of nucleophosmin fused to 14aa of ALK protein

Molecular Weight: 38kDa

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO