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Thermo Scientific™ Lab Vision™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS1849PABX

 View more versions of this product

Catalog No. MS1849PABX


 

Specifications

Description

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody.

Nucleophosmin (NPM)/B23/numatrin is a phosphoprotein associated with cell nucleoli. Treatment of cells with cytotoxic drugs may make nucleophosmin enter nucleoplasm. It is reported that nucleophosmin shuttles continuously between cytoplasm and nucleoli to carry newly synthesized ribosomal proteins into nucleoli. NPM-ALK is a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in anaplastic large cell lymphoma. In acute promyelocytic leukemia NPM gene is fused to RARalpha gene in (5;17) (q33;q12) transition.

Host Species: Mouse

Clone: NA24

Isotype: IgG/κ

Species Reactivity: Human. Others not known.

Epitope: N-terminal

Immunogen: GST fusion protein containing the N-terminal part of nucleophosmin fused to 14aa of ALK protein

Molecular Weight: 38kDa

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Nucleophosmin (NPM) Ab-1
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Murine
IgG kappa
RUO
Primary
Human
Immunohistochemistry (Paraffin)
NA24
Unlabeled
Concentrated
GST fusion protein containing the N-terminal part of nucleophosmin fused to 14 aa of ALK protein
200μL
Cancer and Tumor Biology
Monoclonal