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Tocris™ NSC 23766

Selective inhibitor of Rac1-GEF interaction; antioncogenic

$181.19 - $762.58

Specifications

Product Type NSC 23766
Inhibitors NSC 23766
Molecular Weight 530.97
Purity >96
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Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
216110R Tocris™
216110
10mg Each for $181.19
216150R Tocris™
216150
50mg Each for $762.58
Specifications

Description

Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ∽ 50μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotyes in prostate cancer cells.
  • Chemical Name: N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
  • Formula: C24H35N7.3HCl
  • CAS Number: 1177865-17-6
  • Solubility: Soluble to 100mM in water and to 100mM in DMSO
  • Purity: >99
Description & Specifications

Specifications

NSC 23766
NSC 23766
530.97
>96