Please login to your online account to display your discounted pricing

Tocris™ NPS 2143 hydrochloride

Selective antagonist of the calcium-sensing receptor; orally active calcilytic agent

$237.76 - $1,001.17

Specifications

Product Type NPS 2143 hydrochloride
Inhibitors NPS 2143 hydrochloride
Molecular Weight 445.38
Purity >99
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

362610R

 
tocris™
3626/10
10mg Each for $237.76

362650R

 
tocris™
3626/50
50mg Each for $1,001.17
Description & Specifications

Specifications

Product Type NPS 2143 hydrochloride
Inhibitors NPS 2143 hydrochloride
Molecular Weight 445.38
Purity >99

Selective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells (IC50 = 43nM). Also stimulates parathyroid hormone secretion from bovine parathyroid cells (EC50 = 41nM). Orally active calcilytic compound.

  • Chemical Name: 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino-2-hydroxypropoxy]benzonitrile hydrochloride
  • Formula: C24H25ClNO2.HCl
  • CAS Number: 324523-20-8
  • Solubility: Soluble to 100mM in DMSO and to 10mM in ethanol
  • Purity: >99