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Tocris™ NPS 2143 hydrochloride

Selective antagonist of the calcium-sensing receptor; orally active calcilytic agent

$244.81 - $997.23

Specifications

Product Type NPS 2143 hydrochloride
Inhibitors NPS 2143 hydrochloride
Molecular Weight 445.38
Purity >99
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Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
362610R Tocris™
RDS362610
10mg Each for $244.81
362650R Tocris™
RDS362650
50mg Each for $997.23
Specifications

Description

Selective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells (IC50 = 43nM). Also stimulates parathyroid hormone secretion from bovine parathyroid cells (EC50 = 41nM). Orally active calcilytic compound.
  • Chemical Name: 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino-2-hydroxypropoxy]benzonitrile hydrochloride
  • Formula: C24H25ClNO2.HCl
  • CAS Number: 324523-20-8
  • Solubility: Soluble to 100mM in DMSO and to 10mM in ethanol
  • Purity: >99
Description & Specifications

Specifications

NPS 2143 hydrochloride
NPS 2143 hydrochloride
445.38
>99