Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Notch-1 Ab-1, Mouse Monoclonal Antibody


Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ Notch-1 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1339PABX

 View more versions of this product

Catalog No. MS1339PABX

  • / Each
 

Description & Specifications

Specifications

Cross Reactivity Human
Cross Reactivity Mouse
Isotype IgG2b
Format Concentrated
Regulatory Status RUO
Host Species Mouse
Clone A6
Quantity 200µL
Immunogen Recombinant protein encoding the ligand binding region of human Notch-1
Applications Flow Cytometry
Antigen Notch-1 Ab-1
Research Discipline Neuroscience
Conjugate Unlabeled
Classification Monoclonal
Type Primary
Concentration 1mg/mL

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ Notch-1 Ab-1, Mouse Monoclonal Antibody.

The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals, which include notch-1. notch-2, notch-3, and notch-4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins δ and Serrate have been identified as ligands of notch-1. Mature notch proteins are heterodimeric receptors derived from the cleavage of notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm). Alteration of notch-1 signaling or expression may contribute to tumorigenesis.

Host Species: Mouse

Clone: A6

Isotype: IgG2b

Species Reactivity: Human and Mouse. Others not known.

Epitope: Ligand binding region

Immunogen: Recombinant protein encoding the ligand binding region of human Notch-1

Molecular Weight: 290kDa

Cellular Localization: Membrane

Recommended for:

  • Immunoprecipitation (Not verified)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO