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NOS2 Rat anti-Mouse, Clone: CXNFT, eBioscience™

Rat Monoclonal Antibody

$130.68 - $302.28

Specifications

Antigen NOS2
Clone CXNFT
Host Species Rat
Gene Alias iNOS, nitric oxide synthase 2
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122698 Life Technologies
LS14592080
25μg Each for $130.68
501122699 Life Technologies
LS14592082
100μg Each for $302.28
Specifications

Description

This CXNFT monoclonal antibody reacts to mouse NOS2 (inducible NOS, iNOS). Nitric oxide synthase enzymes catalyze the formation of nitric oxide from L-arginine through an NADPH- and oxygen-dependent mechanism. There are three isoforms of NOS that are encoded by three separate genes. NOS1 (neuronal NOS, nNOS) and NOS3 (endothelial NOS, eNOS) are constitutively expressed, while NOS2 is induced in response to bacterial endotoxins and inflammatory cytokines such as IFN gamma and TNF alpha. NOS2 is expressed by myeloid-derived suppressor cells and M1 macrophages but not alternatively activated M2 macrophages. NOS enzymes are functionally active only when they form homodimers, and dimerization of NOS2 occurs at steady-state concentrations of free Ca2+ such that NOS2 is functionally active when it is produced.
Description & Specifications

Specifications

NOS2
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CXNFT
iNOS, nitric oxide synthase 2
Flow Cytometry (Intracellular Staining),Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL