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Norfloxacin, Thermo Scientific Chemicals

A synthetic fluoroquinolone antibiotic

Supplier:  Thermo Scientific Chemicals J6265203

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Catalog No. AAJ6265203



Description

Description

It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water

Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Keep it refrigerated.
Specifications

Specifications

Norfloxacin
Powder
220°C to 221°C
MFCD00079532
Baccidal; Sebercim
OGJPXUAPXNRGGI-UHFFFAOYSA-N
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
4539
319.33
1 g
Norfloxacin
70458-96-7
C16H18FN3O3
14,6700
Soluble in acetic acid; Also soluble in acetone or cloroform; Slightly soluble in water
CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O
319.336
CHEBI:100246
White to Yellow

Chemical Identifiers

70458-96-7
319.336
OGJPXUAPXNRGGI-UHFFFAOYSA-N
4539
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
C16H18FN3O3
MFCD00079532
Baccidal; Sebercim
CHEBI:100246
CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O
Safety and Handling

Safety and Handling

EINECSNumber : 274-614-4

RTECSNumber : VB5005000

TSCA : No

Recommended Storage : Keep cold

SDS
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RUO – Research Use Only