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Alfa Aesar™ Nitrendipine

L-type calcium channel blocker

Chemical Identifiers

Chemical Name or Material Nitrendipine
CAS 39562-70-4
Molecular Formula C18H20N2O6
Formula Weight 360.36g/mol
MDL Number MFCD00082255
Merck Index 14,6576
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ60841ME

 
alfa aesar™
J60841-ME
500mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Color Yellow to Green
Quantity 500mg
Chemical Name or Material Nitrendipine
CAS 39562-70-4
Physical Form Powder
Molecular Formula C18H20N2O6
Formula Weight 360.36g/mol
MDL Number MFCD00082255
Merck Index 14,6576
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H302-H312-H332
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Health Hazard 3 GHS P Statement
P261-P280-P304+P340-P301+P312-P312-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Call a POISON CENTER or doctor/physician if you feel unwell.
Dispose of contents/container in accordance with local/regional/national/international regulations.
RTECS Number US5653000

Applications
Nitrendipine modulates NMDA receptor channel function in mammalian neurons. Nitrendipine has been shown to inhibit neutrophil adhesion to vascular endothelium. It is used in the treatment of primary hypertension to decrease blood pressure. Nitrendipine is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal′s variant angina.

Solubility
Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Safety and Handling

Warning

GHS P Statement
P261-P280-P304+P340-P301+P312-P312-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Call a POISON CENTER or doctor/physician if you feel unwell.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H302-H312-H332
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.