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Nitrendipine, Thermo Scientific Chemicals
L-type calcium channel blocker
Supplier: Thermo Scientific Chemicals J60841ME
Description
Nitrendipine modulates NMDA receptor channel function in mammalian neurons. Nitrendipine has been shown to inhibit neutrophil adhesion to vascular endothelium. It is used in the treatment of primary hypertension to decrease blood pressure. Nitrendipine is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Specifications
| Nitrendipine | |
| Yellow to Green | |
| MFCD00082255 | |
| 14,6576 | |
| Soluble in DMSO (17.5mg/ml),methanol (15mg/ml),ethyl acetate,and ethanol (25 mM). Insoluble in water. | |
| CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C | |
| 360.366 | |
| CHEBI:7582 | |
| Powder |
| 39562-70-4 | |
| C18H20N2O6 | |
| 500 mg | |
| nitrendipine, bayotensin, baypress, nidrel, nitrendipinum, nitrendipino, bylotensin, nitrendipin, deiten, nitrepin | |
| PVHUJELLJLJGLN-UHFFFAOYSA-N | |
| 5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | |
| 4507 | |
| 360.36 |
Chemical Identifiers
| 39562-70-4 | |
| 360.366 | |
| PVHUJELLJLJGLN-UHFFFAOYSA-N | |
| 4507 | |
| 5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| C18H20N2O6 | |
| MFCD00082255 | |
| nitrendipine, bayotensin, baypress, nidrel, nitrendipinum, nitrendipino, bylotensin, nitrendipin, deiten, nitrepin | |
| CHEBI:7582 | |
| CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C |
Safety and Handling
GHS H Statement
H302-H312-H332
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P312-P330-P363-P501c
H302+H312+H332
EINECSNumber : 254-513-1
RTECSNumber : US5653000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only