missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Please login to your online account to display your discounted pricing
Nigericin sodium salt, 98+%, Thermo Scientific Chemicals
A potassium ionophore
Supplier: Thermo Scientific Chemicals J61349MA
Description
Nigericin sodium salt is a polyether ionophore which catalyzes the electroneutral exchange of alkali metal (K+) for H+ (antiport). It disrupts membrane potential and stimulates ATPase activity in mitochondria. It transports monovalent cations across membranes with the following specificity: K+ >Rb+ >Cs+ >>Na. It kills bacteria by facilitating the diffusion of ions across membranes. It is widely used in studies of the consequences of changes in membrane potential in variable systems.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsNigericin sodium salt is a polyether ionophore which catalyzes the electroneutral exchange of alkali metal (K+) for H+ (antiport). It disrupts membrane potential and stimulates ATPase activity in mitochondria. It transports monovalent cations across membranes with the following specificity: K+ >Rb+ >Cs+ >>Na. It kills bacteria by facilitating the diffusion of ions across membranes. It is widely used in studies of the consequences of changes in membrane potential in variable systems.
Solubility
Soluble in chloroform, methanol or ethanol
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents, acids, bases and heat.
Specifications
| Nigericin sodium salt | |
| White | |
| MFCD00036825 | |
| UN3462 | |
| 14,6541 | |
| Soluble in chloroform, methanol or ethanol | |
| CC1CCC(OC1C(C)C(=O)O)CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC | |
| 724.973 | |
| 746.94 | |
| Powder |
| 28643-80-3 | |
| C40H68O11 | |
| 10 mg | |
| 3892398 | |
| nigericin | |
| DANUORFCFTYTSZ-FBMOGUJMSA-N | |
| (2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2- | |
| 123134611 | |
| ≥98% |
Safety and Handling
GHS H Statement
H301-H315-H319-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H301-H315-H319-H335
DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
RTECSNumber : QT6840000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only