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Alfa Aesar™ Nifedipine, 98%

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells

Manufacturer:  Alfa Aesar™ J6281114

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Catalog No. AAJ6281114



Description

Description

Applications
L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

Solubility
Soluble in acetone, methylene chloride, chloroform, ethyl acetate, dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.

Notes
Light sensitive. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, caustics, aliphatic amines, amides, diethylamine, potassium hydride and potassium hydroxide.
Specifications

Specifications

Nifedipine
171°C to 175°C
21829-25-4
MFCD00057326
nifedipine, procardia, adalat, procardia xl, adalat cc, cordipin, corinfar, fenihidine, citilat, oxcord
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
346.339
CHEBI:7565
Powder
White to Yellow
25g
C17H18N2O6
14,6528
HYIMSNHJOBLJNT-UHFFFAOYSA-N
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
4485
346.33
98%

Chemical Identifiers

21829-25-4
346.339
HYIMSNHJOBLJNT-UHFFFAOYSA-N
4485
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
C17H18N2O6
MFCD00057326
nifedipine, procardia, adalat, procardia xl, adalat cc, cordipin, corinfar, fenihidine, citilat, oxcord
CHEBI:7565
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
Safety and Handling

Safety and Handling

GHS H Statement
H302
Harmful if swallowed.

GHS P Statement
P264-P270-P301+P312-P330-P501a
Wash thoroughly after handling.
Do not eat, drink or smoke when using this product.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : US7975000

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