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Alfa Aesar™ Nifedipine, 98%

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells

Manufacturer:  Alfa Aesar™ J6281106

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Catalog No. AAJ6281106



Description

Description

Applications
L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

Solubility
Soluble in acetone, methylene chloride, chloroform, ethyl acetate, dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.

Notes
Light sensitive. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, caustics, aliphatic amines, amides, diethylamine, potassium hydride and potassium hydroxide.
Specifications

Specifications

Nifedipine
171°C to 175°C
21829-25-4
MFCD00057326
adalat, adalat cc, citilat, cordipin, corinfar, fenihidine, nifedipine, oxcord, procardia, procardia xl
HYIMSNHJOBLJNT-UHFFFAOYSA-N
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
4485
346.33
98%
White to Yellow
5g
C17H18N2O6
14,6528
Soluble in acetone,methylene chloride,chloroform,ethyl acetate,dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
346.339
CHEBI:7565
Powder

Chemical Identifiers

21829-25-4
346.339
HYIMSNHJOBLJNT-UHFFFAOYSA-N
4485
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
C17H18N2O6
MFCD00057326
adalat, adalat cc, citilat, cordipin, corinfar, fenihidine, nifedipine, oxcord, procardia, procardia xl
CHEBI:7565
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
Safety and Handling

Safety and Handling

GHS H Statement
H302
Harmful if swallowed.

P264b-P270-P301+P312-P330-P501c

H302

EINECSNumber : 244-598-3

RTECSNumber : US7975000

TSCA : No

Recommended Storage : Ambient temperatures

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