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NGFR Mouse, Clone: ME20.4, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen NGFR
Clone ME20.4
Host Species Mouse
Species Reactivity Canine, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Sheep
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122781

 
affymetrix
14940080
25μg Each for $143.55

501122782

 
affymetrix
14940082
100μg Each for $361.05
Description & Specifications

Specifications

Antigen NGFR
Clone ME20.4
Host Species Mouse
Species Reactivity Canine, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Sheep
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Microscopy
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody ME20.4 recognizes CD271, a 75kDa type I transmembrane protein that belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily. CD271 is expressed by neurons, Schwann cells, melanocytes, mesenchymal stem/stromal cells, neural crest stem cells, astrocytes, oligodendrocytes, and a subset of lymphoid cells including follicular dendritic cells. CD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9.

The ME20.4 monoclonal antibody recognizes human, non-human primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271.