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Thermo Scientific™ Lab Vision™ NFκ B/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody


Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ NFκB/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1638P1ABX

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Catalog No. RB1638P1ABX

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Description & Specifications

Specifications

Antigen NFkappaB/p65 (Rel A) Ab-1
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Canine
Cross Reactivity Drosophila
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Cross Reactivity Xenopus
Format Concentrated
Formulation Ab Without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide from the C-terminus of human NFkappaB protein
Isotype IgG
Quantity 500µL
Regulatory Status RUO
Research Discipline Transcription Regulation
Type Primary

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ NFκB/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody.

NFκ B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA). The p50/p65 heterodimer is present in the cytoplasm in inactive form bound to its inhibitor, IdeltaB. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFκB which goes to the nucleus inducing gene expression. NFκB was originally identified as transcriptional activator for kappa light chain gene in B cells.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drosophila, Xenopus. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of human NFκB protein

Molecular Weight: 65kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO