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Neural / Glial Antigen 2 (NG2) Mouse anti-Human, Clone: 9.2.27, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $303.05

Specifications

Antigen Neural / Glial Antigen 2 (NG2)
Clone 9.2.27
Host Species Mouse
Gene Alias Chondroitin Sulfate Proteoglycan, MCSP/melanoma chondroitin sulfate proteoglycan
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245580

 
affymetrix
14650480
25μg Each for $129.05

50245581

 
affymetrix
14650482
100μg Each for $303.05
Description & Specifications

Specifications

Antigen Neural / Glial Antigen 2 (NG2)
Clone 9.2.27
Host Species Mouse
Gene Alias Chondroitin Sulfate Proteoglycan, MCSP/melanoma chondroitin sulfate proteoglycan
Species Reactivity Human
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Immunoprecipitation
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 9.2.27 monoclonal antibody reacts with human neural/glial antigen 2, which is also known as melanoma chondroitin sulfate proteoglycan (MCSP). This antigen is composed of a 250kDa N-linked glycoprotein and a >450kDa proteoglycan. NG2 is present on the surface of >90% of malignant melanomas in addition to some non-melanomic tumors. Moreover, NG2 is expressed on glioma cells, as well as on developing and adult oligodendrocyte precursor cells. Studies have demonstrated the involvement of this protein in tumor cell proliferation, adhesion, migration, and invasion. NG2 also functions as a coreceptor for alpha4beta1 integrin. Finally, expression of NG2 can be used as a prognostic marker for disorders such as acral letiginous melanoma and infantile acute myeloid leukemia.

The 9.2.27 antibody has been reported to suppress melanoma tumor growth.