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Nestin Mouse anti-Mouse, Rat, Clone: Rat-401 (Rat401 (4D4)), eBioscience™

Mouse Monoclonal Antibody

$117.48 - $315.48

Specifications

Antigen Nestin
Clone Rat-401 (Rat401 (4D4))
Host Species Murine
Species Reactivity Mouse, Rat
Applications Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013205 Life Technologies
LS14584380
25μg Each for $117.48
5013206 Life Technologies
LS14584382
100μg Each for $315.48
Specifications

Description

The monoclonal antibody Rat-401 recognizes mouse and rat nestin, a Class VI intermediate filament protein (>170 kDa) primarily expressed in neuroepithelial stem cells. Upon neural differentiation, expression is down-regulated and within the adult nervous system is limited to progenitor cells in the cortical subventricular zone, the hippocampal dentate gyrus, dorsal root ganglia satellite cells, and a subpopulation of Schwann cells. Nestin expression is also present in other progenitor cell populations such as pancreatic islet, angiogenic endothelial cells, and bone marrow mesenchymal stem cells. Nestin filaments require vimentin and desmin for assembly into heterodimers and polymers. Upon differentiation, Nestin-containing filaments are replaced by cell type specific intermediate filament proteins, such as GFAP.
Description & Specifications

Specifications

Nestin
Murine
Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
Rat-401 (Rat401 (4D4))
Mouse, Rat
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer