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Alfa Aesar™ Necrostatin-1

A cell-permeable, potent, and selective blocker of necroptosis

Chemical Identifiers

Chemical Name or Material Necrostatin-1
CAS 4311-88-0
Formula Weight 259.33g/mol
MDL Number MFCD00056916
Synonym Nec-1; Necroptotic Inhibitor
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ65341FPL

 
alfa aesar™
J65341-FPL
20mg CALL N/A N/A
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Description & Specifications

Specifications

Sensitivity Light Sensitive
Color Yellow
Quantity 20mg
Chemical Name or Material Necrostatin-1
CAS 4311-88-0
Physical Form Powder
Formula Weight 259.33g/mol
MDL Number MFCD00056916
Synonym Nec-1; Necroptotic Inhibitor
Storage Note 1 2° to 8°C

Applications
Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.

Solubility
Soluble in DMSO (10-25 mg/ml), 100% ethanol (6 mg/ml), and methanol (5 mg/ml).

Notes
Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.

Safety and Handling

2° to 8°C