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Alfa Aesar™ Naringin

A citrus bioflavanoid that inhibits cytochrome P-450 monooxygenase activity

$50.27 - $178.89

Chemical Identifiers

CAS 10236-47-2
Molecular Formula C27H32O14
Molecular Weight (g/mol) 580.539
MDL Number MFCD00148888
InChI Key DFPMSGMNTNDNHN-ODOGPVEPSA-N
Synonym 4',5,7-Trihydroxyflavanone 7-rhamnoglucoside
PubChem CID 74787988
IUPAC Name 7-[(2S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
SMILES CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ6316614 View Documents Alfa Aesar™
J6316614
25g Each for $50.27
 
AAJ6316622 View Documents Alfa Aesar™
J6316622
100g Each for $178.89
 
Description

Description

Applications
A citrus bioflavanoid that inhibits cytochrome P-450 monooxygenase activityNaringin is used to prepare naringin dihydrochalcone, which is about 300-1800 times sweeter than sugar. It is a citrus bioflavonoid reported to inhibit cytochrome P450 monooxygenase activity. It also acts as an inhibitor of cytochrome P450 enzymes. It is employed as an antioxidant, lipid lowering and anticancer agent. In addition to this, it is used in a study to assess aldosterone production by a human adrenocortical cell line and to improve cognitive deficits of Alzheimer′s disease.

Solubility
Soluble in water, alcohol, acetone and warm acetic acid.

Notes
Incompatible with strong oxidizing agents.
Specifications

Chemical Identifiers

10236-47-2
580.539
DFPMSGMNTNDNHN-ODOGPVEPSA-N
74787988
CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O
C27H32O14
MFCD00148888
4',5,7-Trihydroxyflavanone 7-rhamnoglucoside
7-[(2S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

Specifications

White to Yellow
10236-47-2
MFCD00148888
14,6425
DFPMSGMNTNDNHN-ODOGPVEPSA-N
7-[(2S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
74787988
Powder
25g
C27H32O14
102012
4',5,7-Trihydroxyflavanone 7-rhamnoglucoside
CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O
580.539
580.53
Naringin
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : QN6340000

TSCA : TSCA