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Nanog Mouse anti-Human, Clone: hNanog.2, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $355.08

Specifications

Antigen Nanog
Clone hNanog.2
Host Species Murine
Applications Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Western Blot
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013137 Life Technologies
LS14576880
25μg Each for $170.28
5013138 Life Technologies
LS14576882
100μg Each for $355.08
Specifications

Description

The hNanog.2 antibody recognizes human Nanog, a homeobox transcription factor expressed in embryonic stem cells (ESC). Nanog is essential for self-renewal of ESC and the inner cell mass and is throught to function in the same capacity as other factors such as Oct4 and Sox2. Nanog plays a crucial role in embryonic cell fate specification following formation of the blastocyst by regulating proliferation and preventing differentiation. Nanog functions by directly binding DNA consensus sequences to activate or repress transcription. In differentiating ESC, Nanog binds to its own promoter leading to repression of expression. Nanog has been reported to be overexpressed in germ cell tumors of the gonads and central nervous system as well as breast and colorectal cancer.
Description & Specifications

Specifications

Nanog
Murine
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
hNanog.2
Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL