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Thermo Scientific™ NanoDrop™ OneC Microvolume UV-Vis Spectrophotometer

Maximize your productivity with the Thermo Scientific™ NanoDrop™ OneC Spectrophotometer to quantify and qualify samples before your next experiment.

Manufacturer:  Thermo Scientific™ 840274200

Catalog No. 13-400-519

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.



Maximize your productivity with the Thermo Scientific™ NanoDrop™ OneC Spectrophotometer to quantify and qualify samples before your next experiment.

Our next generation Thermo Scientific™ NanoDrop™ OneC microvolume spectrophotometers are pushing the boundaries once again with the Thermo Scientific™ Acclaro™ Sample Intelligence Software that helps you understand the quality of your sample before you use it in downstream applications, bringing you one step closer to success. NanoDrop™ OneC spectrophotometer features a thermostated, stirred cuvette position for additional life science measurements.

Product Features:
  • Full spectrum microvolume UV-Vis spectrophotometer with cuvette position (stirring, 37°C thermostatting, kinetics)
  • Meas. range 0.4 - 27500ng/µL dsDNA
  • 190nm-850nm wavelength meas range
  • Column integrity sensor
  • 2 yr warranty

Quantify and qualify DNA, RNA, and protein samples with only 1-2µL and have full-spectral data in seconds using the Thermo Scientific™ NanoDrop™ OneC Microvolume UV-Vis spectrophotometer.
  • Prevent costly delays — identify contaminants, obtain corrected concentrations, and enjoy success in your downstream applications
  • Collect data fast — Auto-Blank and Auto-Measure modes save time while organizing data
  • Save bench space — user-friendly local control with sleek, standalone design means no PC required

NanoDrop OneC Instrument Highlights
  • Contains both pedestal and cuvette positions to expand experimental flexibility and increase the dynamic range.
  • Measure dilute samples, perform kinetics experiments and take optical density measurements of bacterial cultures.
  • Cuvette position includes temperature control and stirring.

Thermo Scientific™ Acclaro™ Sample Intelligence Software enhances user understanding of sample quality while delivering accurate quantitative measurements. Early identification of contaminants can prevent failure of downstream applications and save days of troubleshooting.
  • Verify sample quality in seconds — identify sample contaminants and obtain corrected concentration results
  • Access information through alerts — receive instant feedback about sample quality with on-demand technical support and guided troubleshooting
  • Rely on accurate results — ensure measurement integrity with embedded sensor and digital image analysis
NanoDrop OneC Enhancements
  • Ergonomic, standalone design — integrated Android™ tablet eliminates the need for a separate computer and provides modern connectivity for seamless data transfer via Wireless*, Ethernet or USB.
  • Auto-Measure and Auto-Blank functions — multi-sample processing can be streamlined with instant measurements that occur when the pedestal arm is down. These functions can be turned ON or OFF with a single tap on the screen.
  • Wider dynamic range — no dilutions required for highly concentrated samples (dsDNA at 27,500ug/µL) with auto-range pathlength technology.
  • Integrated Learning Center — an archive of answers with technical support documents and educational animations at your fingertips.

NanoDrop One/OneC Spectrophotometer capabilities:
  • Wide spectral range (190-850 nm) for measuring a variety of samples types:
    • Peptides (205 nm)
    • DNA and RNA (260 nm)
    • Purified protein (280 nm)
    • Toxicology assays and industrial dyes (490 nm)
    • Gold nanoparticles (520 nm)
    • Colorimetric protein assays (BCA 562 nm, Bradford 595 nm, Modified Lowry 650 nm, Pierce 660 660 nm)
    • Optical Density measurements (600 nm)
  • Combining the patented** sample-retention system with cuvette capability accommodates low and high concentrations (2.0 - 27,500ng/ µL dsDNA and 0.06 - 820mg/mL BSA)
  • Pedestal measurements that require only 0.5 - 2µL of your sample and do not require sample dilution, even for highly concentrated samples
  • Pre-configured methods for DNA, Protein A280, Microarray, Protein and Labels, Pierce 660, Bradford, BCA, and Lowry
  • User-friendly software that includes custom methods and data export capabilities
  • Instrument comes with a 2-year warranty for worry-free support

* Wi-Fi model not available in certain countries - consult your local NanoDrop distributor
**Patents US6628382 and US6809826
Android is a trademark of Google Inc.

For research use only. Not for diagnostic purposes.
All NanoDrop instruments are approved to CE and UL/CSA.


2 year



PR-1 pedestal conditioning solution, PV-1 performance verification solution, USB memory device, Microfiber screen wipe, USA Power Cable
2 year
Product Certifications