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Nalidixic acid, 50 mg/ml in water, sterile-filtered, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals J671948EQ
Description
Nalidixic acid is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. It is used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent)t DNA supercoiling, and chromosome fragmentation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsNalidixic acid is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. It is used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent)t DNA supercoiling, and chromosome fragmentation.
Solubility
Soluble in chloroform (50 mg/ml), ethanol (0.9 mg/ml) at 23°C, methanol (1.3 mg/ml) at 23°C, toluene (1.6 mg/ml) at 23°C, DMSO (≥ 6 mg/ml), and solution of carbonates. Fully miscible in water.
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications
| Nalidixic acid | |
| 389-08-2 | |
| MFCD00006884 | |
| nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus | |
| MHWLWQUZZRMNGJ-UHFFFAOYSA-N | |
| 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid | |
| 4421 | |
| Liquid |
| 50mg/mL in water, sterile-filtered | |
| C12H12N2O3 | |
| 5 x 1 mL | |
| Soluble in chloroform (50mg/ml),ethanol (0.9mg/ml) at 23°C,methanol (1.3mg/ml) at 23°C,toluene (1.6mg/ml) at 23°C,DMSO (? 6mg/ml),and solution of carbonates. Fully miscible in water. | |
| CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O | |
| 232.239 | |
| CHEBI:100147 |
Chemical Identifiers
| 389-08-2 | |
| 232.239 | |
| MHWLWQUZZRMNGJ-UHFFFAOYSA-N | |
| 4421 | |
| 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid |
| C12H12N2O3 | |
| MFCD00006884 | |
| nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus | |
| CHEBI:100147 | |
| CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O |
Safety and Handling
P261-P272-P280g-P285-P302+P352-P304+P341-P333+P313-P342+P311-P363-P501c
H317-H334
EINECSNumber : 206-864-7
RTECSNumber : QN2885000
TSCA : No
storageNote1 : -30° to -10°C
Recommended Storage : Store at -20°C
RUO – Research Use Only