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Alfa Aesar™ N,O-Bis(trimethylsilyl)acetamide, 95%

Chemical Identifiers

Chemical Name or Material N,O-Bis(trimethylsilyl)acetamide
CAS 10416-59-8
Molecular Formula C8H21NOSi2
Formula Weight 203.43g/mol
MDL Number MFCD00008270
UN Number UN2920
Beilstein 1306669
Synonym BSA
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAL0018306

 
alfa aesar™
L00183-06
5g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAL0018314

 
alfa aesar™
L00183-14
25g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAL0018322

 
alfa aesar™
L00183-22
100g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Quantity 5g
Boiling Point 71° to 73°C (35mmHg)
Melting Point −24°C
Quantity 5g
Flash Point 42°C (107°F)
Chemical Name or Material N,O-Bis(trimethylsilyl)acetamide
CAS 10416-59-8
Assay 95%
Molecular Formula C8H21NOSi2
Formula Weight 203.43g/mol
MDL Number MFCD00008270
UN Number UN2920
Beilstein 1306669
Synonym BSA
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H301-H314-H318-H226
Toxic if swallowed.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
Health Hazard 3 GHS P Statement
P210-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage 2° to 8°C
DOT Information Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, FLAMMABLE, N.O.S.
RTECS Number AK3000000
TSCA TSCA

Applications
N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloids and amides. It is employed in the formation of stable trimethylsilyl derivatives. Further, it is used in analytical chemistry for the derivatization of compounds in analysis to increase their volatility and to introduce the trimethylsilyl protecting group in organic synthesis. In addition to this, it is used in the protection of hydroxyl groups in natural products, functional groups in organic intermediates and derivatization reagent for gas chromatography-Mass spectral analysis of phenolic acids in fruits.

Solubility
Miscible with many nonpolar and polar aprotic solvents.

Notes
Air and moisture sensitive. Incompatible with strong oxidizing agents, water and acids.

Safety and Handling

Danger

GHS P Statement
P210-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H301-H314-H318-H226
Toxic if swallowed.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.

2° to 8°C