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Alfa Aesar™ N-Ethylmaleimide, 98+%

Chemical Identifiers

Chemical Name or Material N-Ethylmaleimide
CAS 128-53-0
Molecular Formula C6H7NO2
Formula Weight 125.13g/mol
MDL Number MFCD00005509
UN Number UN2928
Beilstein 112448
Merck Index 14,3822
Synonym 1-Ethyl-1H-pyrrole-2,5-dione; NEM
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAL0035509

 
alfa aesar™
L00355-09
10g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAL0035518

 
alfa aesar™
L00355-18
50g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Melting Point 43° to 46°C
Boiling Point 209° to 211°C
Quantity 10g
Flash Point 73°C (163°F)
Odor Pungent
Chemical Name or Material N-Ethylmaleimide
CAS 128-53-0
Assay ≥98%
Molecular Formula C6H7NO2
Formula Weight 125.13g/mol
MDL Number MFCD00005509
UN Number UN2928
Beilstein 112448
Merck Index 14,3822
Synonym 1-Ethyl-1H-pyrrole-2,5-dione; NEM
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H300-H311-H314-H318-H317
Fatal if swallowed.
Toxic in contact with skin.
Causes severe skin burns and eye damage.
Causes serious eye damage.
May cause an allergic skin reaction.
Health Hazard 3 GHS P Statement
P260-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Remove/Take off immediately all contaminated clothing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOT Information Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, CORROSIVE, ORGANIC, N.O.S.
RTECS Number UX9625000
TSCA TSCA

Applications
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.

Solubility
Soluble in ethanol, water, chloroform, methanol and toluene.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.

Safety and Handling

Danger

GHS P Statement
P260-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Remove/Take off immediately all contaminated clothing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H300-H311-H314-H318-H317
Fatal if swallowed.
Toxic in contact with skin.
Causes severe skin burns and eye damage.
Causes serious eye damage.
May cause an allergic skin reaction.