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Myogenin Mouse, Clone: F5D, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $346.55

Specifications

Antigen Myogenin
Clone F5D
Host Species Mouse
Species Reactivity Canine, Human, Mouse, Rat
Applications Immunocytochemistry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013111

 
affymetrix
14-5643-80
25μg Each for $172.55

5013112

 
affymetrix
14-5643-82
100μg Each for $346.55
Description & Specifications

Specifications

Antigen Myogenin
Clone F5D
Host Species Mouse
Species Reactivity Canine, Human, Mouse, Rat
Applications Immunocytochemistry
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This F5D monoclonal antibody reacts with human, mouse, dog, and rat myogenin, a 34kDa transcription factor. Expressed in skeletal and heart muscle, myogenin is a member of the MyoD family of basic-helix-loop-helix proteins, which also includes MyoD, Myf5, and MRF4. This transcription factor interacts with other helix-loop-helix proteins, which may or may not be muscle-specific. Myogenin plays a significant role in myogenic differentiation, even directing nonmuscle cells to the myogenic lineage. Transforming growth factor-beta (TGFb) and bone morphogenetic protein-2 (BMP2) inhibit myogenin transcriptional activity. Predominantly residing within the nucleus, the subcellular localization of myogenin has been shown to be dependent on differentiation status and cell density. For instance, trafficking of myogenin between the nucleus and cytoplasm has been reported during skeletal muscle differentiation to mediate transcription control.