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Myogenin Mouse, Alexa Fluor 488, Clone: F5D, eBioscience™

Mouse Monoclonal Antibody

$174.24 - $415.80

Specifications

Antigen Myogenin
Clone F5D
Host Species Murine
Applications Immunocytochemistry
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5016764 Life Technologies
LS53564380
25μg Each for $174.24
5016765 Life Technologies
LS53564382
100μg Each for $415.80
Specifications

Description

This F5D monoclonal antibody reacts with human, mouse, dog, and rat myogenin, a 34kDa transcription factor. Expressed in skeletal and heart muscle, myogenin is a member of the MyoD family of basic-helix-loop-helix proteins, which also includes MyoD, Myf5, and MRF4. This transcription factor interacts with other helix-loop-helix proteins, which may or may not be muscle-specific. Myogenin plays a significant role in myogenic differentiation, even directing nonmuscle cells to the myogenic lineage. Transforming growth factor-beta (TGFb) and bone morphogenetic protein-2 (BMP2) inhibit myogenin transcriptional activity. Predominantly residing within the nucleus, the subcellular localization of myogenin has been shown to be dependent on differentiation status and cell density. For instance, trafficking of myogenin between the nucleus and cytoplasm has been reported during skeletal muscle differentiation to mediate transcription control.
Description & Specifications

Specifications

Myogenin
Murine
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
F5D
Immunocytochemistry
Alexa Fluor 488
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.5mg/mL