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Musashi-1 Rat, Clone: 14H1, eBioscience™

Rat Monoclonal Antibody

$143.55 - $346.55

Specifications

Antigen Musashi-1
Clone 14H1
Host Species Rat
Species Reactivity Human, Mouse, Rat
Applications Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013834 Life Technologies
LS14989680
25μg Each for $143.55
5013835 Life Technologies
LS14989682
100μg Each for $346.55
Specifications

Description

This 14H1 monoclonal antibody recognizes human Musashi-1 (MSI-1), a 39kDa RNA binding protein. Musashi-1 is expressed in CNS stem and progenitor cells with decreased expression in differentiating cells. Musashi-1 functions as a translational repressor, directly regulating its target proteins, Numb and p21 (CIP1). Musashi-1 has been shown to be expressed in stem cells in a variety of other tissues such as the gut, stomach, mammary gland, and hair follicles. In addition to normal tissue expression, Musashi-1 expression has been identified in cells from several tumor types, mainly pulmonary and adenocarcinoma, as well as large and small cell carcinomas. Recently, expression of Musashi-1 in ischemic lesions following stroke provides evidence for neurogenesis as well as the role of Musashi-1 in regulating apoptosis.

Musashi-1 is highly conserved and the 14H1 antibody also recognizes mouse and rat Musashi-1.
Description & Specifications

Specifications

Musashi-1
Rat
Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Western Blot
Unlabeled
Store at 2-8°C. Avoid repeated freeze/thaw cycles.
Monoclonal
0.5mg/mL
14H1
Human, Mouse, Rat
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer