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MP Biomedicals Bradykinin


Pro-inflammatory peptide acting through G-protein-coupled receptors

Manufacturer: mp biomedicals  10111205

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Catalog No. ICN10111205

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Description & Specifications

Specifications

Molecular Weight 1060.22
Purity >99%
Quantity 5mg
Format Powder
Sequence H2N-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH
Storage Requirements -20°C
Product Type Bradykinin

Bradykinin activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.

  • Synonyms: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
  • CAS Number: 5979-11-3
  • EC Number: 227-781-2
  • Physical Appearance: White powder
  • Format: Supplied as acetate salt
  • Soluble in 0.1M HOAc (25mg/mL)