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eBioscience™ Mouse TGF beta 1, Recombinant Protein

Mouse Recombinant Protein

$390.05 - $1,825.55

Specifications

Name TGF beta 1
Recombinant Yes
Conjugate Unlabeled
Purity >95%
Purification Method SDS-PAGE
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122731

 
ebioscience™
14834262
5μg Each for $390.05

501122732

 
ebioscience™
14834280
25μg Each for $839.55

501122733

 
ebioscience™
14834282
100μg Each for $1,825.55
Description & Specifications

Specifications

Name TGF beta 1
Recombinant Yes
Conjugate Unlabeled
Purity >95%
Purification Method SDS-PAGE
For Use With (Application) Functional Assays , Cell Culture
Molecular Weight Mature TGFb1 polypeptide has a predicted molecular mass of 12,794. On reducing SDS-PAGE the protein migrates as a 13kDa polypeptide and on non-reducing SDS page the cystine-linked homodimer migrates as a 25kDa protein.
Storage Requirements Store at less than or equal to -70°C.

Mouse TGF beta 1 (Transforming Growth Factor beta 1) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF beta 1 is a 25 kDa protein with each subunit containing 112 aa residues. TGF beta 1 is secreted from the many cell types in a complex with LAP (Latency Associated Peptide) and also with LTBP (latent TGF beta binding protein). Disassociation is thought to happen in the extracellular matrix via proteases and/or integrins. Regulatory T cells are a recently identified source of TGF beta 1 thought to be a key player in their suppressive functions. TGF beta 1 binds through TGF beta receptors (of which there is a large family). The protein is highly conserved across all mammalian species.