Interleukin 5 (IL-5) is a T cell-derived factor that promotes the proliferation, differentiation and activation of eosinophils. In mice, IL-5 is also a growth and differentiation factor for B cells. Various names previously used to describe IL-5 include: Tcell replacing factor (TRF), B cell growth factor II (BCGFII), B cell differentiation factor μ (BCDF μ), eosinophil differentiation factor (EDF) and eosinophil colony-stimulating factor (Eo-CSF). Biologically active IL-5 is a disulfide-linked homodimer. Rat IL-5 is 94% and 70% identical to mouse and human IL-5, respectively.
Assay Type: Solid Phase Sandwich ELISA Sample Type/Volume Required: Cell Culture Supernates (50μL), Serum (50μL) Sensitivity: 7pg/mL Specificity: Natural and recombinant mouse IL-5 Cross Reactivity: <50% cross-species reactivity observed with species tested. <0.5% cross-reactivity observed with available related molecules.