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Mouse IL-17 Quantikine ELISA Kit, R&D Systems

$808.39 - $1,939.37

Specifications

Product Type Solid Phase Sandwich ELISA
Gene ID (Entrez) 16171
Sample Type Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma
Sample Volume Cell Culture Supernates (50μL), Serum (50μL), EDTA Plasma (50μL), Heparin Plasma (50μL)
Sensitivity 5pg/mL
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Products
Catalog Number Mfr. No. Packaging Quantity Price Quantity    

M1700

 
r & d systems
RDSM1700
2 Plates Each for $808.39

SM1700

 
r & d systems
RDSSM1700
6 Plates Each for $1,939.37
Description & Specifications

Specifications

Product Type Solid Phase Sandwich ELISA
Gene ID (Entrez) 16171
Sample Type Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma
Sample Volume Cell Culture Supernates (50μL), Serum (50μL), EDTA Plasma (50μL), Heparin Plasma (50μL)
Sensitivity 5pg/mL
Species Mouse
Specificity Natural and recombinant mouse IL-17
Sufficient For Sufficient materials to run ELISAs on at least six 96-well plates

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

Assay Type: Solid Phase Sandwich ELISA
Sample Type/Volume Required: Cell Culture Supernates (50μL), Serum (50μL), EDTA Plasma (50μL), Heparin Plasma (50μL)
Sensitivity: 5pg/mL
Specificity: Natural and recombinant mouse IL-17
Cross Reactivity: <50% cross-species reactivity observed with species tested. Cross-reactivity observed with 1 or more available related molecules.