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eBioscience™ Mouse CD254 (RANK Ligand), Recombinant Protein

Mouse Recombinant Protein

$201.55 - $491.55

Specifications

Name CD254 (RANK Ligand)
Recombinant Yes
Conjugate Unlabeled
Purity >90%
Purification Method reducing SDS-PAGE
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

5018532

 
ebioscience™
14-8612-62
5μg Each for $201.55

5018533

 
ebioscience™
14-8612-80
25μg Each for $491.55
Description & Specifications

Specifications

Name CD254 (RANK Ligand)
Recombinant Yes
Conjugate Unlabeled
Purity >90%
Purification Method reducing SDS-PAGE
Source E. coli
For Use With (Application) Cytokine Bioassays
Molecular Weight 20kDa
Storage Requirements Store at less than or equal to -70°C.

RANK Ligand (Receptor Activator for Nuclear Factor κB Ligand), also known as TNF-related activation-induced cytokine (TRANCE), along with RANK are members of the TNF superfamily. RANK-L can be found as a soluble protein expressed by activated T lymphocytes, which plays a role in dendritic cell maturation. In addition it has also been shown to be cleaved by TACE (TNF-α convertase) releasing an ectodomain variant of the cell bound form. Lastly RANK-L is expressed as a Type II transmembrane protein expressed by osteoblast lineages. The receptor RANK, located on osteoclastic and dendritic cells can recognize all forms of RANK-L. RANK-L plays a critical role in bone development and mineralization. High levels of RANK-L have been associated with degenerative bone diseases.