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Mouse anti-Von Willebrand Factor, Clone: SPM577, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23481001MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23481001

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Description & Specifications

Specifications

Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Format Purified
Monoclonal or Polyclonal Monoclonal
Isotype IgG1, κ
Cross Reactivity Human
Clone SPM577
Host Species Mouse
Conjugate Unlabeled
Immunogen Recombinant human vWF fragment
Gene ID (Entrez) 7450
Reconstitution Protein A purified
Test Specificity von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Primary or Secondary Primary
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen Von Willebrand Factor
Regulatory Status RUO
Gene Accession No. P04275
Concentration 1mg/mL
Purification Method Purified
Quantity 0.1mg