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Mouse anti-TAG-72, Clone: CC49, Novus Biologicals™

Manufacturer:  Novus Biologicals Canada NBP23138301MG

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Catalog No. NBP23138301


 

Disclaimers:

For Research Use Only


Specifications Description & Specifications

Specifications

TAG-72
CC49
Unlabeled
PBS with 0.05% BSA.
Purified TAG-72 protein
Purified
RUO
Primary
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Bovine,Canine,Human,Rat
ELISA,Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot
0.2mg/mL
Purified
Murine
IgG1, κ
0.1mg
Store at 4°C. Do not freeze.
Monoclonal
Protein A purified