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Mouse anti-TAG-72, Clone: CC49, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23138302MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23138302

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Description & Specifications

Specifications

Antigen TAG-72
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone CC49
Concentration 0.2mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Canine
Cross Reactivity Human
Cross Reactivity Rat
Format Purified
Formulation PBS with 0.05% BSA.
Host Species Mouse
Immunogen Purified TAG-72 protein
Isotype IgG1, κ
Purification Method Purified
Quantity 0.2mg
Regulatory Status RUO
Storage Requirements Store at 4°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Test Specificity Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Reconstitution Protein A purified