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Mouse anti-TAG-72, Clone: CC49, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23138302MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23138302

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Description & Specifications

Specifications

Conjugate Unlabeled
Formulation PBS with 0.05% BSA.
Immunogen Purified TAG-72 protein
Format Purified
Host Species Mouse
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Cross Reactivity Bovine
Cross Reactivity Canine
Cross Reactivity Human
Cross Reactivity Rat
Storage Requirements Store at 4°C. Do not freeze.
Isotype IgG1, κ
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Regulatory Status RUO
Quantity 0.2mg
Concentration 0.2mg/mL
Clone CC49
Test Specificity Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Purification Method Purified
Antigen TAG-72
Reconstitution Protein A purified