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Mouse anti-SUMO1, Clone: SPM571, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23480502MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23480502

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Description & Specifications

Specifications

Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Format Purified
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Quantity 0.2mg
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Reconstitution Protein A purified
Antigen SUMO1
Host Species Mouse
Immunogen Recombinant human SUMO1 protein
Regulatory Status RUO
Gene ID (Entrez) 7341
Test Specificity This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. Expceted to show broad species reactivity.
Concentration 1mg/mL
Gene Accession No. P63165
Isotype IgG1, κ
Purification Method Purified
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone SPM571
Conjugate Unlabeled
Cross Reactivity Human