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Mouse anti-SUMO1, Clone: SPM571, Azide Free, Novus Biologicals™

Manufacturer:  Novus Biologicals Canada NBP23480502MG

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Catalog No. NBP23480502


 

Disclaimers:

For Research Use Only


Specifications Description & Specifications

Specifications

SUMO1
SPM571
Unlabeled
10mM PBS. Does not contain BSA. Azide Free.
Murine
IgG1, κ
0.2mg
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Monoclonal
This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. Expceted to show broad species reactivity.
Human
ELISA,Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot
1mg/mL
Purified
P63165
Recombinant human SUMO1 protein
Purified
RUO
Primary
7341
Protein A purified