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Mouse anti-SUMO1, Clone: SM1/495, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23471601MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23471601

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Description & Specifications

Specifications

Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Format Purified
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Gene Accession No. P63165
Clone SM1/495
Cross Reactivity Human
Test Specificity This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. Expceted to show broad species reactivity.
Purification Method Purified
Immunogen Recombinant human SUMO1 protein
Concentration 1mg/mL
Isotype IgG1, κ
Antigen SUMO1
Quantity 0.1mg
Primary or Secondary Primary
Reconstitution Protein A purified
Gene ID (Entrez) 7341
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Conjugate Unlabeled