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Mouse anti-Renal Cell Carcinoma (gp200), Clone: 66.4.C2 (PN-15), Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519902MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519902

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Description & Specifications

Specifications

Antigen Renal Cell Carcinoma (gp200)
Format Purified
Formulation PBS with 0.05% BSA. Protein G purified.
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2b, κ
Quantity 0.2mg
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Cross Reactivity Equine
Cross Reactivity Human
Gene Accession No. Q16790
Immunogen Fresh
Regulatory Status RUO
Gene ID (Entrez) 4065
Test Specificity Recognizes a glycoprotein of ∽200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Clone 66.4.C2 (PN-15)
Conjugate Unlabeled
Host Species Mouse
Purification Method Purified
Monoclonal or Polyclonal Monoclonal
Concentration 0.2mg/mL