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Mouse anti-NCAM-1/CD56, Clone: SPM489, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23436401ML

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 Disclaimers

For Research Use Only

Catalog No. NBP23436401

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Description & Specifications

Specifications

Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Format Purified
Conjugate Unlabeled
Immunogen Membrane preparation of a small cell lung carcinoma
Isotype IgG1, κ
Gene ID (Entrez) 4684
Primary or Secondary Primary
Regulatory Status RUO
Clone SPM489
Host Species Mouse
Concentration 0.2mg/mL
Formulation PBS with 0.05% BSA.
Quantity 0.1mL
Storage Requirements Store at 4°C. Do not freeze.
Reconstitution Protein A purified
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Antigen NCAM-1/CD56
Purification Method Purified
Cross Reactivity Human