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Mouse anti-NCAM-1/CD56, Clone: SPM489, Azide Free, Novus Biologicals™

Manufacturer:  Novus Biologicals Canada NBP23441202MG

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Catalog No. NBP23441202


 

Disclaimers:

For Research Use Only


Specifications Description & Specifications

Specifications

NCAM-1/CD56
SPM489
Unlabeled
10mM PBS. Does not contain BSA. Azide Free.
Membrane preparation of a small cell lung carcinoma
Purified
RUO
Primary
4684
Protein A purified
ELISA,Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot
1mg/mL
Purified
Murine
IgG1, κ
0.2mg
Store at -20 to -80°C. Avoid freeze-thaw cycles.
Monoclonal
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Human