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Mouse anti-NCAM-1/CD56, Clone: SPM489, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23441201MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23441201

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Description & Specifications

Specifications

Cross Reactivity Human
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Conjugate Unlabeled
Immunogen Membrane preparation of a small cell lung carcinoma
Clone SPM489
Gene ID (Entrez) 4684
Concentration 1mg/mL
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Antigen NCAM-1/CD56
Storage Requirements Store at -20 to -80°C. Avoid freeze-thaw cycles.
Format Purified
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Regulatory Status RUO
Quantity 0.1mg
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Isotype IgG1, κ
Purification Method Purified
Reconstitution Protein A purified