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Mouse anti-NCAM-1/CD56, Clone: 123C3, Novus Biologicals™

Manufacturer:  Novus Biologicals Canada NBP21518402MG

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Catalog No. NBP21518402


 

Disclaimers:

For Research Use Only


Specifications Description & Specifications

Specifications

NCAM-1/CD56
123C3
Unlabeled
PBS with 0.05% BSA. Protein G purified.
Murine
IgG1, κ
0.2mg
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Monoclonal
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
ELISA,Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot
0.2mg/mL
Purified
P13591
The immunogen for this CD56 antibody was a membrane preparation of a small cell lung carcinoma.
Purified
RUO
Primary
4684
Human,Rat,Zebrafish