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Mouse anti-NCAM-1/CD56, Clone: 123c3.D5+123A8, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23428005ML

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For Research Use Only

Catalog No. NBP23428005

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Description & Specifications

Specifications

Cross Reactivity Human
Format Purified
Formulation PBS with 0.05% BSA.
Gene Accession No. P13591
Immunogen Membrane preparation of a small cell lung carcinoma
Purification Method Purified
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Antigen NCAM-1/CD56
Host Species Mouse
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG1, κ
Primary or Secondary Primary
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Reconstitution Protein A purified
Concentration 0.2mg/mL
Conjugate Unlabeled
Quantity 0.5mL
Storage Requirements Store at 4°C. Do not freeze.
Gene ID (Entrez) 4684
Clone 123c3.D5+123A8