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Mouse anti-NCAM-1/CD56, Clone: 123c3.D5+123A8, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23428005ML

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 Disclaimers

For Research Use Only

Catalog No. NBP23428005

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Description & Specifications

Specifications

Antigen NCAM-1/CD56
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone 123c3.D5+123A8
Concentration 0.2mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation PBS with 0.05% BSA.
Gene Accession No. P13591
Host Species Mouse
Immunogen Membrane preparation of a small cell lung carcinoma
Isotype IgG1, κ
Purification Method Purified
Quantity 0.5mL
Regulatory Status RUO
Storage Requirements Store at 4°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 4684
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Reconstitution Protein A purified