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Mouse anti-NCAM-1/CD56, Clone: 123c3.D5+123A8, Novus Biologicals™

Manufacturer: novus biologicals canada  NBP23428001ML

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For Research Use Only

Catalog No. NBP23428001

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Description & Specifications


Regulatory Status RUO
Cross Reactivity Human
Immunogen Membrane preparation of a small cell lung carcinoma
Monoclonal or Polyclonal Monoclonal
Formulation PBS with 0.05% BSA.
Antigen NCAM-1/CD56
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Storage Requirements Store at 4°C. Do not freeze.
Isotype IgG1, κ
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Format Purified
Conjugate Unlabeled
Clone 123c3.D5+123A8
Reconstitution Protein A purified
Concentration 0.2mg/mL
Quantity 0.1mL
Primary or Secondary Primary
Gene ID (Entrez) 4684
Purification Method Purified
Gene Accession No. P13591