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Mouse anti-NCAM-1/CD56, Clone: 123c3.D5+123A8, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23451902MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23451902

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Description & Specifications

Specifications

Formulation 10mM PBS. Does not contain BSA. Azide Free.
Antigen NCAM-1/CD56
Format Purified
Host Species Mouse
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Immunogen Membrane preparation of a small cell lung carcinoma
Purification Method Purified
Quantity 0.2mg
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 4684
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Clone 123c3.D5+123A8
Conjugate Unlabeled
Gene Accession No. P13591
Isotype IgG1, κ
Storage Requirements Store at -20 to -80°C. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Reconstitution Protein A purified
Concentration 1mg/mL
Cross Reactivity Human