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Mouse anti-NCAM-1/CD56, Clone: 123c3.D5+123A8, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23451901MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23451901

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Description & Specifications

Specifications

Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Quantity 0.1mg
Isotype IgG1, κ
Regulatory Status RUO
Conjugate Unlabeled
Cross Reactivity Human
Gene ID (Entrez) 4684
Clone 123c3.D5+123A8
Reconstitution Protein A purified
Format Purified
Monoclonal or Polyclonal Monoclonal
Antigen NCAM-1/CD56
Immunogen Membrane preparation of a small cell lung carcinoma
Primary or Secondary Primary
Host Species Mouse
Gene Accession No. P13591
Storage Requirements Store at -20 to -80°C. Avoid freeze-thaw cycles.
Purification Method Purified
Concentration 1mg/mL
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.