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Mouse anti-NCAM-1/CD56, Clone: 123A8, Novus Biologicals™

Manufacturer: novus biologicals canada  NBP23427905ML

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For Research Use Only

Catalog No. NBP23427905

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Description & Specifications


Format Purified
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Cross Reactivity Human
Conjugate Unlabeled
Host Species Mouse
Concentration 0.2mg/mL
Isotype IgG1, κ
Immunogen Membrane preparation of a small cell lung carcinoma
Clone 123A8
Reconstitution Protein A purified
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation PBS with 0.05% BSA.
Gene ID (Entrez) 4684
Gene Accession No. P13591
Antigen NCAM-1/CD56
Storage Requirements Store at 4°C in the dark.
Quantity 0.5mL
Purification Method Purified