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Mouse anti-NCAM-1/CD56, Clone: 123A8, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23451802MG

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For Research Use Only

Catalog No. NBP23451802

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Description & Specifications

Specifications

Format Purified
Immunogen Membrane preparation of a small cell lung carcinoma
Isotype IgG1, κ
Primary or Secondary Primary
Conjugate Unlabeled
Monoclonal or Polyclonal Monoclonal
Test Specificity This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Applications ELISA
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Cross Reactivity Human
Antigen NCAM-1/CD56
Gene Accession No. P13591
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Quantity 0.2mg
Gene ID (Entrez) 4684
Storage Requirements Store at -20 to -80°C. Avoid freeze-thaw cycles.
Concentration 1mg/mL
Reconstitution Protein A purified
Clone 123A8
Purification Method Purified
Regulatory Status RUO